Weight reduction increases adipose tissue lipoprotein lipase responsiveness in obese women.

Increase of adipose tissue lipoprotein lipase activity with weight loss.

Obese subjects have elevated adipose tissue lipoprotein lipase activity per fat cell when compared with lean control subjects. This enzyme, which is rate limiting for the uptake and storage of lipoprotein triglyceride in adipose tissue, has been shown to be further elevated in a group of previously obese subjects who had been weight stable at a reduced weight for 4-28 mo. In the present prospec...

Lipoprotein lipase in human adipose tissue.

Determinants of Human Adipose Tissue Lipoprotein Lipase

to percent of ideal body weight (r = 0.76, P < 0.001 for controls; r = 0.67, P <0.05 for diabetics) and to fat cell size (r = 0.71, P <0.01 for controls; r = 0.85, P <0.01 for diabetics. Postprandial-stimulated insulin secretion was related to diet-induced changes in lipoprotein lipase in control subjects; both were dependent upon the amount of dietary carbohydrate. In contrast, the diabetic pa...

Lipoprotein lipase of chicken adipose tissue.

In recent publications (l-3), the clearing factor of postheparin plasma has been identified with a lipoprotein lipase obtained from rat, rabbit, and calf heart and rat and rabbit adipose tissue. This enzyme catalyzes the hydrolysis of the triglyceride moiety of chylomicrons and low density @-lipoproteins. The hydrolysis of simple triglyceride emulsions is also catalyzed by lipoprotein lipase bu...

Increase of Adipose Tissue Lipoprotein Lipase

A B S T R A C T Obese subjects have elevated adipose tissue lipoprotein lipase activity per fat cell when compared with lean control subjects. This enzyme, which is rate limiting for the uptake and storage of lipoprotein triglyceride in adipose tissue, has been shown to be further elevated in a group ofpreviously obese subjects who had been weight stable at a reduced weight for 428 mo. In the p...